Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Colon cancer is the third most common cause of cancer globally and leads to
many deaths. Conventional chemotherapy has severe side effects and toxicities, which
are significant challenges for cancer treatment. Current therapy has an essential concern
of target specificity. In colon cancer, the primary concern is to deliver the drug to
cancer cells in the colon in a reproducible and predictable manner. The oral route has
its limitations. The drug delivered through this route gets degraded or may not be
subsequently absorbed to produce the effects or lessen them before reaching the colon.
Nanocarriers empowered the delivery of chemotherapeutics at specific sites and
enhanced cellular penetrability. Within the organism, the cytotoxic substance will
quickly accumulate. The present chapter focuses on the different nanostructures
designed to deliver the drugs to treat colon cancer.
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Authors:Bentham Science Books