Nanoparticles and Nanocarriers Based Pharmaceutical Formulations

Author(s): Vivek Shrivastava, Bhavisha Patel and Akhlesh K. Jain * .

DOI: 10.2174/9789815049787122010017

Biological Approaches to Nanoparticles Synthesis and their Applications in the Development Of Herbal Formulations

Pp: 436-454 (19)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

This chapter focuses on the sustainable environment for the synthesis of nanoparticles using microorganisms, enzymes, or botanical extracts as an alternative to chemical synthesis, and their subsequent application in herbal drug delivery systems. The objective is to emphasize the rapid, straightforward, and reliable synthesis of nanoparticles using a novel, preferably eco-friendly process. Herbal drugs are gaining prominence due to their ability to treat chronic diseases, such as arthritis and hypertension. However, several constraints, such as poor solubility, poor bioavailability, and low oral absorption, have restricted their use. Nanoparticle-loaded phytochemicals disperse conveniently in liquid and thus perforate easily. Merging nanotechnology with herbal medicine is required to produce better therapeutics with improved activity in the fight against long-term chronic disorders. Tissue engineering is another significant application of nanotechnology. 

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