Polymeric Nanoparticles as Drug Delivery System: Basic Concepts and Applications

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Delivering drugs through various delivery systems into the body for successful treatment of diseases is most entrancing deeds for the pharmaceutical analyst. Conventional drug delivery systems have various hindrances like loss of medication and poor bioavailability of drugs. Polymer-based nanocarriers such as polymeric nanoparticles upgrade bioavailability of drug, delivery of drug to specific site and improve solubility of drugs. They are widely explored as controlled, precise, sustained and continuous release systems for drug delivery and are easily incorporated and appropriate for practically all parts of nanomedicines and bring new trust in field of drug conveyance by redesigning drug viability and diminishing drug toxicity. This chapter mainly focuses on polymers and techniques engaged with advancement of polymer-based nanoparticles and their applications in therapeutic intervention. 

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