Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Interpretation of molecular differences and intricacy at multiple stages, for
instance proteome, genome, epigenome, metabolome, and transcriptome is needed for a
thorough understanding of disease and human health. Biology has been reliant on data
produced at these stages, which is collectively referred to as multi-omics data, after the
emergence of sequencing techniques. Among all the aspects of biology, rapid
development in high-throughput data initiation has enabled to carry out research on
multi-omics systems biology. Metabolomics, proteomics, and transcriptomics data can
provide answers to the targeted biological queries about the expression of metabolites,
proteins, and transcripts, independently. A concise summary of multi-omics data
sources, challenges in datasets integration, and visualization portals is also discussed.
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Authors:Bentham Science Books