Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Localized controlled drug delivery systems (LCDDSs) have become the
main topic in drug delivery, tissue engineering and pharmaceutical science by
enhancing formulations and processes of controlled delivery. The side effects and
problems of materials/biomaterials are critical and may lead to several issues, such as
reducing the effective drug dose, delaying the treatment process, and not having a
particular continuous treatment. Therefore, composites composed of hybrid
materials/biomaterials with excellent release properties, biocompatibility, stability and
biodegradability, with local adjusted release rates, are an alternate choice for protective
drug delivery. Several approaches to fabricating composite-based LCDDSs include
emulsification-solvent evaporation, spray drying, electrospraying, supercritical fluids
processing, microfluidics, and nanoprecipitation/solvent displacement and emulsion.
This chapter describes the advances in micro/nanoscaled composite-based LCDDSs
and their fabrication methods.
Keywords:
Drug delivery, Fabrication methods, Microfluidics, Microscaled composites, Nanoscaled composites, Release properties.
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Authors:Bentham Science Books