Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
World health organization (WHO) has acknowledged the problem of multidrug resistance (MDR) bacteria as an endemic and widespread problem globally. MDR
in LMICs represents one of the biggest threats to global health and is one of the
greatest current challenges in infectious disease research. High mortality/morbidity
rates of MDR infections are mainly due to the lack of timely, rapid detection and
treatment of the causative pathogen. Molecular mechanism conferring MDR against
most common treatment options includes mutations in antibiotics’ susceptible genes at
one or many sites. A number of methods, including culture-based, nucleic acid-based
amplification of resistance conferring genes, and immunological based assays have
been developed to detect MDR. Each method has defined specificity, sensitivity and
time around to detect MDR infections in clinical settings.
Keywords:
Antimicrobial Resistance, Detection of MDR, Multi-drug resistance bacteria (MDR), MDR infections
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Authors:Bentham Science Books