Thermophilic Fungi and their Applications in Biotechnology

Pp: 359-383 (25)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Thermophilic fungi survive at a growth temperature above 45°C. Although
widely spread in the terrestrial region, they have remained underexplored, diverging
from other thermophiles of eubacteria and archaea. Thermophilic fungi elicited a lot of
interest due to their ability to produce thermostable and thermotolerant compounds
with practical applications in the field of biotechnology. Studies on growth kinetics,
physiology, supplement uptake, and protein breakdown rate in thermophilic fungi have
provided important information on these fungi. Thermophilic fungi can degrade
biomass such as polysaccharides into monomers. The characteristics of their enzymes
show contrasts among species, just as among strains of comparative species. Some
extracellular compounds separated from thermophilic fungi are commercially
produced, and a couple of others have the potential due to financial advantages.
Thermophilic fungal genes encoding lipase, protease, and various other vital enzymes
have been cloned and overexpressed in heterologous fungi for understanding the
mechanisms of their natural thermostability and catalysis.

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Authors:Bentham Science Books