An Epidemiological Update on COVID -19

Author(s): Kailasam Saravana Mani * .

DOI: 10.2174/9789815050325122010011

A Randomized Trial of Hydroxychloroquine as Post-exposure Prophylaxis for COVID-19

Pp: 55-62 (8)

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* (Excluding Mailing and Handling)

  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Research revealed that in vitro activity ofchloroquine and the derivative molecule of hydroxychloroquine is against the infection caused by the SARS-CoV and SARS-CoV-2. The US FDA approved the use of both hydroxychloroquinesulfate and chloroquine phosphate for the critical patients of COVID-19. The clinical trials supported that the hydroxychloroquine did not substantially reduce the system severity in non-hospitalized persons. Moreover, it also produces severe side effects like drowsiness, hypokalaemia, nausea, convulsions, shock, and even death.

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