Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part I

Author(s): Anas Tarik Alhamdany*, Ali Khidher Abbas and Mohammed Hussain Al-Mayahy

DOI: 10.2174/9789815036510122010016

Infectious Diseases: Pharmaceutical Nanoscience Targeted Drug Delivery

Pp: 268-291 (24)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Infectious diseases are one of the greatest challenges of our new era. Due to their high incidence and outbreak rate, they can affect human health. Furthermore, the use of conventional drugs to treat infectious diseases is gradually being exhausted due to increasing rates of resistance. Herbal medicines and natural ingredients may also be a good resource for drug production. Several innovations, including the development of nano-drug delivery systems, have new mechanisms of action and various loadings for herbal and non-herbal treatments; this helps decrease the pathogenicity of infectious diseases. In addition, these nano-drug delivery systems provide a good opportunity to improve the efficacy of herbal and non-herbal treatments. They have also been used to deliver target medicinal agents, increase solubility, improve bioavailability, extend half-life for herbal and non-herbal treatments, increase stability, minimize adverse effects, and tissue engineering. Nanocarriers are advanced engineering tailors that control the physicochemical properties of nanoparticles for infectious diseases, leading to targeting by passive or active mechanisms. In this chapter, we highlight the advances in nanocarriers loaded with herbal and nonlherbal agents for treating infectious diseases.

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