Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part I

Author(s): Abubakar Bishir Daku and Asma Abdullah Nurul * .

DOI: 10.2174/9789815036510122010007

Pharmaceutical Nanoscience: Pulmonary Drug Delivery System

Pp: 76-103 (28)

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  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Pulmonary diseases impose an immense burden on global health. Asthma, cystic and idiopathic pulmonary fibrosis, pulmonary hypertension, lung cancer, and chronic obstructive pulmonary diseases (COPD) are among the diseases that require efficient pulmonary drug delivery. Targeted-drug delivery refers to the delivery of a drug or a therapeutic agent to a certain tissue or organ; this can be achieved through pulmonary drug delivery (PDD) with nanomaterials. Nanomaterials are made from polymers, ceramics, metals, and biological materials into different sizes and structures. Nanomaterials for PDD entail nanoparticles of therapeutic ingredients, including herbalbased drugs and nanocarriers of the therapeutic bioactive substance. These types of materials used in managing pulmonary diseases are discussed in this chapter.

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