Advances in Organic Synthesis

Author(s): Shoji Hara

DOI: 10.2174/978160805198410602010049

Fluorination Using Hypervalent Halogen Fluorides

Pp: 49-60 (12)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Among various hypervalent halogen fluorides, BrF3, IF5, and ArIF2 have been successfully used to introduce fluorine atoms into molecules selectively. Characteristic features and representative fluorination reactions involving these reagents are shown.

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