Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
The bioconjugated AgNPs present various applications starting from
advanced molecular medicine agents, drug delivery vectors, gene transfection,
bioimaging and contrast enhancement agents, and as anticancer chemotherapeutics.
Mainly, the theranostic applications of AgNPs combined with the therapeutic effect of
the conjugated biomolecule result in advanced applications. The most recent state-o-
-the-art applications of bioconjugated or biogenic AgNPs include the magnetic imaging
of vital life processes, cellular internalization of bioactive ingredients or therapeutics,
DNA repair and gene transfection in molecular medicine for correcting the anomalies
at the genetic level. The conjugation with AgNPs causes a considerable improvement
in the therapeutic efficacy of anticancer chemotherapeutics owing to targeted release
coupled with the physiological changes associated with the interaction of biological
systems with AgNPs that triggers redox stress and heightened cellular response. The
present chapter deals with the applications of AgNPs conjugated to biological
ingredients or biogenic AgNPs in various fields.
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Authors:Bentham Science Books