Systemic Lupus Erythematosus: A Systematic Approach to Arthritis of Rheumatic Diseases

Author(s): Syuichi Koarada*, Makiko Takayama, Kouki Takedomi, Jun Hirano, Hijiri Hirose, Yuumi Maeda, Yuiko Miyajima, Honoka Mouri and Yukiko Takeyama

DOI: 10.2174/9789815050653122040008

Extra-Articular Soft Tissue and Muscular Involvement in Systemic Lupus Erythematosus

Pp: 175-220 (46)

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  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Soft tissue lesions in systemic lupus erythematosus (SLE) include various
lesions such as subcutaneous edema, synovitis of the joint, edema of the joint capsule,
tenosynovitis, tendon rupture, muscular, and vascular involvement. The synovium of
bursa is also affected. Ultrasound and MRI are especially important for the evaluation
of soft tissue lesions because of the low sensitivity of conventional radiography. The
soft tissue lesions of SLE are diverse and widespread, and understanding their
pathophysiology can help diagnose whether the lesions are of SLE origin or a
complication of other factors. Knowing the soft tissue lesions of SLE can also help us
to deal with the wide variety of lesions in SLE patients. In this article, we summarize
the variety of extra-articular soft tissue lesions.

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