Systemic Lupus Erythematosus: A Systematic Approach to Arthritis of Rheumatic Diseases

Author(s): Syuichi Koarada* and Sachiko Soejima

DOI: 10.2174/9789815050653122040006

Cartilaginous and Capsular Changes in Systemic Lupus Erythematosus

Pp: 104-156 (53)

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* (Excluding Mailing and Handling)

  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Cartilaginous and capsular lesions in systemic lupus erythematosus (SLE),
such as diffuse joint space narrowing (JSN) and synovial proliferation, are usually
mild. Erosions and pressure cause destruction of cartilages in SLE due to misalignment
of joint structures. However, cartilage changes and synovial proliferation are seen in
lupus arthropathy. Especially in rhupus, which is thought to be a complication of
rheumatoid arthritis, cartilaginous and synovial changes are significant findings. Joint
effusions and intra-articular calcifications may also be seen. This chapter will focus on
intra-articular lesions, category “C” in SLE.

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