Medical Applications of Beta-Glucan

Author(s): Betül Gürünlü

DOI: 10.2174/9789815039238122010018

Beta Glucan and Rheumatoid Arthritis (RA)

Pp: 152-156 (5)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Rheumatoid arthritis is encountered in 3 out of 10000 people every year
worldwide. It is usually seen between the ages of 35 and 50. If precautions are not
taken, it may lead to synovial inflammation, destruction of bone and cartilage. Finally
disability occurs in the later stages of the disease. It can shorten the patient’s life span
by 10 years. The previous studies show that β-glucan alone decreased both the hind
paw swelling and the arthrogram on days 21 and 28 of supplementation in rats. In vivo
studies lead to the potential application of (1→3)-β-d-glucan derivatives in treating
human rheumatoid arthritis 

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