Medical Applications of Beta-Glucan

Author(s): Betül Gürünlü

DOI: 10.2174/9789815039238122010013

Beta Glucan for Healing of Bedsores, Wounds, Burns

Pp: 101-114 (14)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Highly purified yeast-derived insoluble β-(1 → 3)-d-glucan efficiently
inhibited adipogenic differentiation, promoted wound healing, and significantly
reduced skin irritation [1,2]. β-glucans can be used on the skin for dermatitis, bed sores,
wrinkles, wounds, eczema, burns, radiation burns, and diabetic ulcers. β-glucan wound
dressings show a suitable wound therapeutic agent with superior stability and
demonstrate resistance to wound proteases. This review explains new developments
and progression on identifying the healing properties of β-glucans for wounds in vitro
and in vivo and their safety and effectiveness remedy for non-healing wounds or other
chronic dermatological diseases. 

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