Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Vascular cognitive impairment (VCI) encompasses vascular dementia (VaD) and is the second leading form of dementia after Alzheimer’s disease (AD) plaguing the elderly population. VaD is a progressive disease that affects cognitive abilities, especially executive functioning. At present VaD lacks suitable animal models, which constrain the progress of identification of molecular and cellular mechanisms of the disease and developing suitable interventions. In this chapter, we will present and discuss the experimental animal models that have been used for VaD studies. The limitations and strengths of these models, along with important research findings, are also addressed.
Keywords:
CADASIL, Cognition, 2-VO, Vascular Dementia, Vascular Cognitive Impairment, White Matter.
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Authors:Bentham Science Books