Recent Advances in Molecular and Translational Medicine: Updates in Precision Medicine

Author(s): James Reigle*, Khyati Mehta and Somchai Chutipongtanate

DOI: 10.2174/9789815036756121010010

Metabolomics and Precision Medicine

Pp: 118-133 (16)

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* (Excluding Mailing and Handling)

  • * (Excluding Mailing and Handling)

Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Metabolomics is a growing “omics” field in investigational research and clinical care. Metabolomics is the study of metabolome, including both endogenous and exogenous small molecules generated in the body viametabolic processes. This discipline is young compared to its complements, such as genomics or transcriptomics. However, it promises to be a powerful tool for understanding normal and diseased physiological states and informing clinicians in diagnosing and treating patients. This chapter summarizes the concept of metabolomics, describes the metabolomic approaches, and provides a practical workflow of metabolomic data analysis to illustrate the current and potential applications of metabolomics in precision medicine.

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