Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Flavonoids are naturally sourced compounds found in many substances consumed as food and have beneficial effects on human health. Chalcones, essential members of the flavonoid family, have also attracted many researchers' attention due to their wide range of pharmacological effects. In this chapter, the antiinflammatory, antidiabetic, and antidepressant activities of the natural compounds in the structure of chalcones and the compounds synthesized with the help these compounds will be discussed. It has been written after a literature review of the articles published between 2000 and 2020 and aims to be a guide for designing new active drug ingredients.
Keywords:
Aldose reductase, Alpha glucosidase, Antidepressant, Antidiabetic, Antiinflammatory, Butein, Chalcones, Cyclooxygenase, Dipeptidyl peptidase-IV, Heme oxygenase-1, Interleukins, Isoliquiritigenin, Kinases, 5-Lipoxygenase, Monoamine oxidase, Noradrenalin, Protein tyrosine phosphatase 1B, Serotonin, Sodium-glucose cotransporter 2, Tumour necrosis factor-alpha.
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Authors:Bentham Science Books