Tetracyclic Benzocarbazoles and Derivatives: Synthesis and Applications

Pp: 158-196 (39)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Tetracyclic benzocarbazoles are examples of nitrogen-containing heterocycles, which display interesting pharmacological activities and physicochemical properties. This chapter aims to bring some examples about the synthesis of bezocarbazoles, mostly benzo[a]carbazoles (including the dihydro and tetrahydro derivatives), with interesting properties. This chapter also includes aza-pterocarpans and aza-coumestans, which are structurally similar to benzo [a] carbazoles, although their analogous natural products are formed through different biosynthetic pathways. Being aware of the potential interest of these compounds, many efforts have been made for the development of new methodologies to carry out their synthesis and will be discussed below.

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