Cellular and Molecular Biology of Autism Spectrum Disorders

Author(s): Ivo Paclt, Anna Strunecka

DOI: 10.2174/978160805196011001010001

Autism Spectrum Disorders: Clinical Aspects

Pp: 1-16 (16)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Autism spectrum disorders (ASD) are a group of related neurodevelopmental disorders, which includes autism (autistic disorder), Asperger syndrome, Rett syndrome, pervasive developmental disorder-not-otherwise specified (PDD-NOS), and childhood disintegrative disorder (CDD). This chapter provides the review of recent knowledge about clinical symptoms and criteria for diagnosis of heterogeneous symptoms of ASD. An alarming increase in the prevalence of ASD is of great concern to practicing pediatricians and psychiatrists. Some people attribute the increases over time in the frequency of ASD to factors such as new administrative classifications, changing diagnostic criteria, and heightened awareness. It is evident, that no single factor or a simple explanation can account for the increase. ASD are highly genetic and multifactorial, with many risk factors acting together. There is no therapy of the core symptoms of ASD at present. Several studies suggest that 50-75% of children with ASD are using complementary alternative medicine. Families and clinicians need access to theoretical and clinical evidence to assist them in the choice of therapies.

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