Introduction to Molecular Genomics

Author(s): Maryam Javed, Asif Nadeem and Faiz-ul Hassan

DOI: 10.2174/9781681089256121010009

Digital Genomic Era

Pp: 104-127 (24)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

This chapter proposes a brief description of the Role of Bioinformatics in the Post-Genomic Era; Digital Sequence Repositories; From the World of 1D to the era of 3D (Protein Structures); Functional Genomics; Sequence Alignment, Phylogeny, and concept of gene evolution; Sequence and structural alignment; Genomics of personalized medicine; CADD: Computer-Aided Drug Designing; Big Data Analysis; Responsible Genomic data sharing.

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