Cardiac Resynchronization Therapy: An Established Pacing Therapy for Heart Failure and Mechanical Dyssynchrony

Author(s): Ana Martin and Antonio Berruezo

DOI: 10.2174/978160805030711101010083

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Novel Indications of Cardiac Resynchronization Therapy: Patients in Atrial Fibrillation, with Narrow QRS Complex and in Functional Class II

Pp: 83-89 (7)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Randomized clinical trials have shown important clinical benefits from cardiac resynchronization therapy, in addition to those obtained with optimal medical treatment, in the advanced heart failure population. However, the criteria for inclusion in these trials are restrictive and only a small proportion of heart failure patients are candidates. The logical next step is to expand this therapy and its possible benefits to heart failure patients in less advanced stages of the disease, with narrow QRS and in atrial fibrillation. In this chapter we review the available findings on the use of this therapy in these subsets of patients.

Keywords:

Heart failure, Cardiac Resynchronization Therapy, Atrial Fibrillation, Narrow QRS Complex

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