Cardiac Resynchronization Therapy: An Established Pacing Therapy for Heart Failure and Mechanical Dyssynchrony

Author(s): Adelina Doltra and Marta Sitges

DOI: 10.2174/978160805030711101010024

Echocardiographic Evaluation of Ventricular Dyssynchrony

Pp: 24-32 (9)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Despite single center studies have suggested that mechanical markers of LV synchrony could predict outcome after CRT, these results have not been reproduced in the multicentric setting and indeed, failure of this markers as predictors of CRT response has been shown. This paradox underscores the limited reproducibility and variability of the currently proposed dyssynchrony analysis techniques. The echocardiographic techniques for the study of dyssynchrony will be discussed in this chapter, pointing out the evidence supporting the use of each method as well as their limitations.

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