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SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Heart failure is a very prevalent disease in the general population, but more so in the elderly. It has a very high morbidity and mortality and it is a growing public health problem. Half of the patients with heart failure have a reduced left ventricular ejection fraction and fewer have a left bundle branch block, which is our currently best selection criterion to identify electrical and mechanical dyssynchrony. When these patients are severely symptomatic despite adequate medical treatment of their heart failure, implantation of a biventricular pacemaker can resynchronize the ventricles and induce a reverse remodelling of the left ventricle and marked symptomatic improvement.
Keywords:
Epidemiology of heart failure, ventricular dyssynchrony, electrical dyssynchrony, mechanical, dyssynchrony, left bundle branch block, QRS complex
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Authors:Bentham Science Books