Frontiers in Nano and Micro-Device Design for Applied Nanophotonics, Biophotonics and Nanomedicine

Author(s): A. Guillermo Bracamonte

DOI: 10.2174/9781681088563121010016

Precision Nanomedicine Based on Genomics and Drug Delivery Systems

Pp: 122-138 (17)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Precision nanomedicine based on advanced diagnosis by personalized analysis with, for example, the incorporation of genomics and specific biomarker tracking have allowed faster diagnosis and application of treatments. With controlledsize cargo nanoparticles, potential applications were also devised for targeted drug delivery, in addition to new enzymatic approaches addressing targeted delivery for targeted DNA repairs. Another novel gene therapy is also discussed. Moreover, we show, for personalized drug assay tests, how design-led to bioassays within microfluidic four-organ-chip devices in order to evaluate compatibilities and effects according to the nature and response of the organism.

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