Abstract
As cardiovascular diseases remain the leading cause of mortality worldwide, a large number of clinical trials are under development, investigating the safety and efficacy of RNA therapeutics in clinical conditions. Nanomedicine based drug delivery systems are currently the new avenue for the treatment of CVDs, providing great advantages to the treatment regime of CVDs. Currently, antisense therapy DNA- and RNA-based and microRNAs are widely applied therapeutic strategies to regulate gene expression and its effect on CVDs. In this review, different biological-based targeting therapies for cardiovascular diseases and their outcomes are discussed.
Keywords: DNA, miRNA, Nanomedicine, Nanoparticles, RNA interference, siRNA.
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