Demystifying COVID-19: Understanding the Disease, Its Diagnosis and Treatment

Author(s): Ozgur Karcioglu *, Selman Yeniocak and Mandana Hosseinzadeh

DOI: 10.2174/9781681087788121010012

COVID-19 Pneumonia and ARDS: The Real Killer?

Pp: 179-206 (28)

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Abstract

Pneumonia and its major complication, acute respiratory distress syndrome (ARDS), are the outstanding causes of morbidity and mortality attributed to the SARSCoV-2. Angiotensin-converting enzyme 2 (ACE2) receptor is commonly found in the alveolar cells of the lung, causing common respiratory symptoms in COVID-19. In addition, the development of respiratory failure, ARDS, and the need for a mechanical ventilator is precipitated by an undertreated pneumonia. ARDS is a condition associated with many disease processes, which causes reduced lung compliance and severe hypoxemia. For early diagnosis and treatment, attention should be paid to the risk of developing ARDS in patients whose disease duration lasts for longer than one week.

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