Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Fluorine chemistry is an important area that made a significant impact on drug discovery development, which can be seen by a large number of drugs in the market containing this chemical element. The success of drugs containing fluorine atoms in its structures is due to its chemical properties compared to the other elements, providing several advantages in drug discovery. Some of these advantages are better metabolic stability, avoiding undesired metabolizations, and improving the bioavailability of the drugs, among others. Due to its importance in drug discovery, the exercises below are focused on fluorine chemistry.
Keywords:
Bioactive compounds, Catalyst, Chemical transformations, Combinatorial chemistry, Drugs, Exercises, Fluorine, Heteroaromatic compounds, Medicinal chemistry, Molecules, Reaction conditions, Reagents, Retrosynthetic analysis, Substances, Synthesis, Synthons.
Recommended Chapters
We recommend
Authors:Bentham Science Books