Abstract
Combinatorial chemistry is a methodology developed based on the synthesis of many compounds (hundreds, thousands, or even millions) in a simple chemical process building libraries of these compounds. In medicinal chemistry, an essential factor is the number of different molecules to be produced. For obtaining a leading compound and later a candidate drug, the biological evaluation of thousands of compounds is necessary. Therefore, the exercises below are based on combinatorial chemistry.
Keywords: Bioactive compounds, Combinatorial chemistry, Chemical transformations, Drugs, Exercises, Heteroaromatic compounds, Medicinal chemistry, Molecules, Reaction conditions, Reagents, Retrosynthetic analysis, Substances, Synthesis, Synthons.
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