Exercises in Organic Synthesis Based on Synthetic Drugs

Author(s): Marcus Vinícius Nora de Souza

DOI: 10.2174/9789811487569120010005

Heteroaromatic Substances

Pp: 114-132 (19)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Heteroaromatics are substances having one or more atoms in the aromatic ring other than the carbon atom. This class of compounds is fundamental in developing new drugs, being present in a large number of drugs and bioactive compounds. Some of these cores are listed below, and it is worth noting that due to their immense structural variety, we mentioned only the most common ones. The exercises of this item we based on the formation of different heteroaromatic substances, and it is up to the reader to identify the respective nuclei.

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