Exercises in Organic Synthesis Based on Synthetic Drugs

Author(s): Marcus Vinícius Nora de Souza

DOI: 10.2174/9789811487569120010003

Organizing Synthetic Routes and Identifying Reagents

Pp: 47-69 (23)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

In this chapter, the exercises below are based on two themes. First, exercises based on the synthesis of several drugs and bioactive compounds used to treat various diseases. Therefore, several reaction conditions are presented. However, these conditions are disordered, and it is up to the reader to order them. The other theme is to identify reagents used for the preparation of a specific target molecule. This type of training is essential because it allows the reader to contact different types of reagents and chemical transformations and use them in a sequentially correct way.

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