Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Diabetes mellitus, a metabolic disorder, characterized by chronic hyperglycemia results from defects in insulin secretion, insulin action, or both. Insulin is an anabolic peptide hormone that possesses pleiotropic activity. It can hinder with multiple physiological processes by either upregulating or downregulating various metabolic intracellular pathways. The complex insulin signaling system makes it vital in a variety of biological responses. This chapter describes the biochemistry of type 2 diabetes mellitus, as well as the features underlying its pathophysiology.
Keywords:
Diabetes, Glucose Uptake, Insulin, Insulin Receptor, Insulin Resistance, Metabolic Disorder.
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Authors:Bentham Science Books