Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. TB is one of the top ten causes of death in the world and it is highly prevalent, characterized by the constant occurrence of drug-resistant cases, and confounded by the incidence of respiratory diseases caused by nontuberculous mycobacteria (NTM). The anti-TB drugs commonly used are insufficient and have multiple adverse effects. Therefore, a new strategy to eradicate this infectious disease is required. The implementation of new anti-TB drugs together with host-directed therapy (HDT) can decrease the duration of treatment and improve the TB patients’ health. It is proposed that natural products are an enormous source of bioactive compounds to treat TB. They can be new anti-TB drugs or agents for HDT.
Keywords:
Allicin, Antimycobacterial compounds, Baicalin, α-Mangostin, Host- Directed Therapy (HDT), Nordihydroguaiaretic acid, Pasakbumin A, Tuberculous and nontuberculous mycobacteria, (10-15) Tuberculosis.
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Authors:Bentham Science Books