Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Angiogenesis is a vital step for complete organ engineering, and the microenvironment is one of the four basic elements of tissue engineering. Microenvironment factors such as oxygen content and stress are key dynamic factors that can trigger the variations of angiogenesis. We may induce the formation of beneficial blood vessels and prevent the formation of pathological blood vessels by precisely regulating the microenvironment. In this chapter, we will elaborate the interaction between vascular endothelial cells and the extracellular microenvironment and summarize the influence of various microenvironment factors on angiogenesis. The finding that microenvironment factors play such a concerted role in angiogenesis suggests that incorporating microenvironment factors into tissue engineering might accelerate the development of novel therapeutics.
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Authors:Bentham Science Books