Perinatal Cardiology-Part 1

Author(s): Maya Reddy and Daniel L. Rolnik

DOI: 10.2174/9789811446801120010005

Cardiovascular Development

Pp: 21-35 (15)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

An understanding of normal cardiovascular development is essential to appreciating the abnormalities seen in congenital heart disease. The cardiovascular system develops within the mesoderm and through the process of folding, and establishment of the body axis, patterning and laterality it transforms from blood islands into the primitive heart tube and then the complex cardiac structures that supply the fetus. This chapter will discuss the embryological formation of the cardiovascular system and how deviations from normal development result in common cardiac defects.

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