Post-Transplant Diabetes Mellitus: Evaluation and Management

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Abstract

Diabetes mellitus affects up to 50% of renal transplant recipients. The incidence of hyperglycemia is high in the early transplant period due to surgery and the exposure to immunosuppressant medications. Patients who develop post-transplant diabetes mellitus (PTDM) are at increased risk of cardiovascular events, infections, graft loss, and mortality. Pre- and post-transplant screening is essential for early detection and management of individuals at high risk for PTDM. This chapter aims to review the latest evidence on the epidemiology, risk factors, guidance on screening, management of the disease and its complications. New international consensus guidelines on diagnosis, current research, as well as quality improvement options will be discussed.

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