Frontiers in Drug Safety

Author(s): L. O. Demirezer and E. Ucakturk

DOI: 10.2174/9781681086750118010011

Adulteration of Food Supplements and Analytical Methodologies for their Quality Control

Pp: 122-139 (18)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Medicinal plant extracts are complex mixtures containing many compounds. Their therapeutic properties may be due to the cumulative or synergistic effects of contained compounds. The adulteration or substitution of the herbal products especially food supplements is crucial problem in herbal products industry. Adulteration or substitution may be deliberate or accidental. Valuable herbal products are substituted with similar low quality products and used as adulterant which may or may not have any therapeutic potential as that of original product. The quality control studies are very important to provide active, high quality and safe food supplement. Therefore, fast, specific, accurate, inexpensive, and high throughput analytical methods are needed. Some chromatographic and spectroscopic techniques are used for identification and quantification of bioactive compounds, impurities, contaminants, and also other compounds present in the food supplements. The chromatographic fingerprint analysis offers significant advantages in analytical methods because of the complex and multi component matrix of the food supplements. Screening of the content and quantification of food supplements can be possible in a single fingerprint run.

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