Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Carbon nanotubes (CNTs), a carbon allotrope with various physicochemical properties, have gained worldwide interest since last two decades. CNTs are made up of cylindrical shaped graphene foils with nanometric dimension and several micrometres in length. The application of CNTs in the field of pharmacy and medicine is based on their large surface area capable to adsorb or conjugate various classes of drugs, genes, vaccines, and antibodies. This review focuses on the applicability of CNTs as targeted drug delivery vehicle considering the biopharmaceutics and toxicokinetics including advantages, obstacles, and perspectives of various CNTs.
Keywords:
Biodistribution, Carbon nanotubes, CNS targeting, Drug targeting, Gene therapy, Lymphatic targeting, Macrophage targeting, PEGylated CNTs, Pharmacokinetics, Toxicity, Tumor targeting, Vaccine delivery.
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Authors:Bentham Science Books