Current and Future Developments in Nanomaterials and Carbon Nanotubes

Author(s): Mohammad Faiyaz Anwar, Neelam Yadav and Swati Jain

DOI: 10.2174/9781681085951118010009

Carbon Nanotubes in Drug Delivery

Pp: 184-207 (24)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Carbon nanotubes are one of the most commonly used nanomaterials in research field and consumer industries. They have attained popularity in biomedical applications pertaining to novel drug delivery carriers, as building blocks for tissue regeneration as well as probes for bio-imaging and bio-sensing. Both multi-walled and single walled CNTs have been employed for therapeutic activity for the treatment of several diseases such as cancer therapy, Neurodegenerative Diseases and Alzheimer Syndrome via multiple approaches. Potential application of CNTs as nano-carrier is their ability to translocate through cellular membranes, facilitate their use for the delivery of therapeutically active molecules resembling cell-penetrating peptides. This chapter highlights the importance of CNTs as a vehicle for delivering wide variety of payloads including drugs, small organic molecules, oligonucleotides, proteins, siRNA, vaccines and nutrients. We have focussed on demonstrating their synthesis and functionalization as important procedural steps for creating a smart and intelligent system for delivery.

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