Tropical Diseases: An Overview of Major Diseases Occurring in the Americas

Author(s): Maria Rosangela Cunha Duarte Coelho, Georgea Gertrudes de Oliveira Mendes Cahu, Viviane Martha Santos de Morais and Ana Cecília Cavalcanti de Albuquerque

DOI: 10.2174/9781681085876117010018

Hepatitis C

Pp: 359-372 (14)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Viral hepatitis are the major cause of liver transplants in the world - especially for hepatitis C (HCV) disorder that now affects over 185 million people in every continent. Initially known as hepatitis non-A non-B HCV was elucidated in 1989 as an etiologic agent. Since then HCV infection acquired special importance among the causes of liver disease particularly among HIV patients on antiretroviral therapy which presents significant morbidity and mortality from liver disease. The natural history of HCV is characterized by a silent evolution often the disease is diagnosed decades after the infection and usually in advanced stage. Hepatitis C has an important impact on global public health accounting for approximately 350,000 deaths per year.

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