Frontiers in Respiratory Medicine

Author(s): David P. Breen and Mohammed Ahmed

DOI: 10.2174/9781681085913117010014

Airway Stenting in Benign and Malignant Diseases

Pp: 196-214 (19)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Airway stenting is an important technique for the treatment of central airway obstruction and is a major component of an integrated Interventional Pulmonology service. Indications for this intervention can be broadly divided into malignant and benign conditions. Malignant airway obstruction is the commonest indication and can happen due to endobronchial tumors or external compression. Benign conditions include stenosis, fistula and airway malacia. An important consideration in benign conditions is patient longevity. Two groups of stents are available- silicon and metallic. Each is associated with advantages and disadvantages and the choice of stents depends on a number of factors including airway and disease related factors, physician choice and expertise and the available equipment within the endoscopy unit. Silicone stents require rigid bronchoscopy for placement while metallic stents can be deployed using flexible bronchoscopy. Irrespective of prosthesis type, stent related complications occur and include migration, stent obstruction from mucus, tumor ingrowth or granulation tissue and stent fracture. Finally, novel drug eluting and biodegradable stents are being studied with promising early results.

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