Advances in Physicochemical Properties of Biopolymers (Part 2)

Author(s): María Victoria Tuttolomondo, Maria Lucia Foglia, Juan Manuel Galdopórpora and Martin Federico Desimone

DOI: 10.2174/9781681085449117010011

Approaches for Improving the Mechanical Properties of Collagen Biomaterials

Pp: 354-370 (17)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Collagen is a natural constituent of the extracellular matrix of tissues. It is well known that, when prepared without additives, diluted collagen hydrogels present poor mechanical properties limiting their use in tissue engineering. Hence, collagen's structural properties need to be enhanced. For this purpose, this chapter presents an overview of the recent advances and alternatives developed to improve the mechanical properties of collagen biomaterials.

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