Abstract
SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.
Abstract
Regenerative medicine generally aims at re-establishing the normal functions by replacing the damaged body parts through stem cells or other biomedical approaches. The tremendous opportunities of mesenchymal stem cells (MSCs) in regenerative medicine have long been recognized. However, this potential “off-theshelf” therapeutic product is still facing daunting challenges. In this chapter, we intend to update the recent progresses and highlight the opportunities and the key challenges in the field. Our discussion has direct implications for identifying new directions for the future basic research as well as clinical applications of MSCs.
Keywords:
Autoimmune diseases, Bone and cartilage diseases, Cell surface markers, Cell therapy, Cell transplantation, Clinical trial, Degenerative diseases, Immunomodulation, Mesenchymal stem cells (MSCs), “Off-the-shelf” therapeutic product, Pre-clinical investigation, Regenerative medicine, Safety profile, Tissue repair, Tissue engineering, Translational applications.
Recommended Chapters
We recommend
Authors:Bentham Science Books