Frontiers in Anti-Infective Drug Discovery

Author(s): Eduardo M. Del Aguila, Laidson P. Gomes, Cyntia S. Freitas, Patricia R. Pereira and Vânia F. Paschoalin

DOI: 10.2174/9781681082912117050005

Natural Antimicrobials in Food Processing: Bacteriocins, Peptides and Chitooligosaccharides

Pp: 55-108 (54)

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

Studies on bioactive proteins and peptides, as well as their potential applications, have continuously increased over the last 20 years. They can be found in all living organisms, from prokaryotes to eukaryotes, and have been detected in different food matrices, maybe the most useful and reliable sources of these molecules. These proteins are referred to as bioactive compounds since they can modify several cellular bioprocesses in order to improve human health human health. Bioactive molecules can occur naturally or can be released from a principal protein after chemical or enzymatic hydrolysis or food fermentation. Bioactive peptides and proteins derived from food matrices or released from microorganisms can present intrinsic antihypertensive, hormone-like, antimicrobial, anti-cancer or antioxidant activities. There is a large demand for natural preservatives and for minimally processed food, researchers have intensified the search for bioactive peptides and proteins, especially those with antimicrobial properties, which are powerful substitutes for conventional food preservatives. This chapter describes the features of antimicrobial peptides and their combination to polymeric materials for food preservation by preventing microorganism proliferation. For this purpose, the bioactive molecules are complexed to chitosan bioactive molecules with chitosan biofilms, creating an antimicrobial packaging. Despite the changes that can occur in the physical properties of these biofilms, the incorporation of antimicrobial peptides to bioplastic biofilms could guarantee the quality and safety of foodstuffs, contributing in extending their shelf life.

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