Role of Cartilage Regeneration in the Management of Early Knee Arthritis: Current Concepts

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Abstract

SHS investigation development is considered from the geographical and historical viewpoint. 3 stages are described. Within Stage 1 the work was carried out in the Department of the Institute of Chemical Physics in Chernogolovka where the scientific discovery had been made. At Stage 2 the interest to SHS arose in different cities and towns of the former USSR. Within Stage 3 SHS entered the international scene. Now SHS processes and products are being studied in more than 50 countries.

Abstract

In this chapter, we discuss review cartilage restoration surgery in the setting of early knee osteoarthritis (OA). We introduce an algorithmic approach to determining treatment and discuss procedures including microfracture, autologous matrix-induced chondrogenesis (AMIC®), osteochondral autograft transfer (OATS), osteochondral allografting (OCA), autologous chondrocyte implantation (ACI)/matrixassisted chondrocyte implantation (MACI), and stem cell therapy. These techniques have particular advantages and disadvantages. The authors share their approach and outline the protocol for postoperative rehabilitation.

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