a)Vazhappilly, C.G.; Saleh, E.; Ramadan, W.; Menon, V.; Al-Azawi, A.M.; Tarazi, H.; Abdu-Allah, H.; El-Shorbagi, A.N.; El-Awady, R. Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types.
Invest. New Drugs, 2018, 1-10.
b)El-Shorbagi, A.N.; El-Naggar, M.; Tarazi, H.; Chaudhary, S.; Abdu-Allah, H.; Hersi, F.; Omar, H. Bis-(5-substituted-2-thiono-1,3,5-thiadiazinan-3-yl) butane as a scaffold of anti-proliferative activity, blended by a multicomponent process.
Med. Chem. Res., 2018,
27(4), 1103-1110.
c)Abdu-Allah, H.H.; Abdel-Moty, S.G.; El-Awady, R.; El-Shorbagi, A.N. Design and synthesis of novel 5-aminosalicylate (5-ASA)-4-thiazolinone hybrid derivatives with promising antiproliferative activity.
Bioorg. Med. Chem. Lett., 2016,
26(7), 1647-1650.
d)El-Shorbagi, A.A.; Abdel-Moty, S.G.; Ahmed, A.N.; Takayama, H.; Kitajima, M.; Aimi, N.; Sakai, S. The antiviral (RNA & DNA) profile of some incomplete C-nucleosides inspired from natural ß-carboline (pyrido [3,4-b] indole) scaffold; pharmacology of the intermediates in the total synthesis.
Pharma Chem., 2015,
11, 87-92.
e)El-Shorbagi, A-N.A.; Husein, M.A. Synthesis and investigation of antihypertensive activity using anaesthetizednormotensive nonhuman primates of some 2-aryl-4-(substituted) pyrimido-[1,2-a] benzimidazoles.
Pharma Chem., 2015,
7(4), 190-200.
f)El-Shorbagi, A-N.A.; Husein, M.A. An approach to hypertension crisis: Evaluation of new fused banzazoles; 2-arylethenyl and 2,4-bis(arylethenyl) derivatives derived from 2,4-dimethylpyrimido [1,2-a] benzimidazole.
Pharma Chem., 2015,
7(5), 319-328.
g)Amin, E.N.; Abdel-Alim, A.A.; Abdel-Moty, S.G.; El-Shorbagi, A.N.; Abdel-Rahman, M.Sh. Synthesis of new 4,5-3(2H)pyridazinone derivatives and their cardiotonic, hypotensive, and platelet aggregation inhibition activities.
Arch. Pharm. Res., 2010,
33(1), 25-46.
h)El Bialy, S.A.; Abdelal, A.M.; El-Shorbagi, A.N.; Kheira, S.M. 2, 3-Bis(5-alkyl-2-thiono-1, 3, 5-thiadiazin-3-yl) propionic acid: one-pot domino synthesis and antimicrobial activity.
Arch. Pharm. (Weinheim), 2005,
338(1), 38-43.
i)Abdel-Moty, S.G.; Sakai, S.; Aimi, N.; Takayama, H.; Kitajima, M.; El-Shorbagi, A.; Ahmed, A.N.; Omar, N.M. Synthesis of cytotoxic 1-polyhydroxyalkyl-β-carboline derivatives.
Eur. J. Med. Chem., 1998,
32(12), 1009-1017.
j)Abd-Elrahman, M.I.; Ahmed, M.O.; Ahmed, S.M. aboul-Fadl, T.; El-Shorbagi, A. Kinetics of solid state stability of glycine derivatives as a model for peptides using differential scanning calorimetry.
Biophys. Chem., 2002,
97(2-3), 113-120.
k)Abdu-Allah, H.; Abdelmoez, A.; Tarazi, H.; El-Shorbagi, A-N.; El-Awady, R. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent
in vitro and
in vivo anti-inflammatory hybrids.
Bioorg. Chem., 2019,
103378[
http://dx.doi.org/10.1016/j.bioorg.2019.103378]
l)Aboul-Fadl, T.; El Shorbagi, A.N. New carriers for representative peptides and peptide drugs.
Arch. Pharm. (Weinheim), 1997,
330(11), 327-332.
m)Aboul-Fadl, T.; El-Shorbagi, A.N.; Hozien, Z.A.; Sarhan, A.W. Investigation of alkylating, antineoplastic and anti-HIV potentials of the chalcones: 2-(3-arylpropenoyl)benzimidazole and their corresponding N1-methyl derivatives.
Boll. Chim. Farm., 2000,
139(5), 228-234.
n)Aboul-Fadl, T.; Hussein, M.A.; El-Shorbagi, A.N.; Khallil, A.R. New 2H-tetrahydro-1, 3, 5-thiadiazine-2-thiones incorporating glycine and glycinamide as potential antifungal agents.
Arch. Pharm. (Weinheim), 2002,
335(9), 438-442.
o)El-Shorbagi, A.N. New tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives as potential antimicrobial agents.
Arch. Pharm. (Weinheim), 2000,
333(9), 281-286.
p)Mohamed, M.H.; El-Shorbagi, A-N.A. (±)-termisine, a novel lupine alkaloid from the seeds of Lupinus termis.
J. Nat. Prod., 1993,
56(11), 1999-2002.
q)El-Shorbagi, A-N.A.; Sakai, S-I.; El-Gendy, M.A.; Omar, N.; Farag, H.H. Imidazo [2,1-b] benzothiazoles. I.
Chem. Pharm. Bull. (Tokyo), 1988,
36(12), 4760-4768.
r)Emara, S.; El-Gindy, A.; El-Shorbagi, A-N.A.; Hadad, G. Utility of copper (II) oxide as a packed reactor in flow injection assembly for rapid analysis of some angiotensin converting enzyme inhibitors.
Anal. Chim. Acta, 2003,
489(1), 115-123.
s)Emara, S.; Razee, S.; El-Shorbagi, A-N.; Masujima, T. Flow injection method for the determination of methotrexate with a column-packed oxidizing agent.
Analyst (Lond.), 1996,
121(2), 183-188.
t)Abdel-Alim, A.A.; El-Shorbagi, A.N.; Abdel-Moty, S.G.; Abdel-Allah, H.H. Synthesis and anti-inflammatory testing of some new compounds incorporating 5-aminosalicylic acid (5-ASA) as potential prodrugs.
Arch. Pharm. Res., 2005,
28(6), 637-647.
[
http://dx.doi.org/10.1007/BF02969351] [PMID:
16042070]
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