Combinatorial Chemistry & High Throughput Screening

Author(s): Rajavel Srinivasan, Shao Q. Yao and Dawn S.Y. Yeo

DOI: 10.2174/1386207043328463

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Chemical Approaches for Live Cell Bioimaging

Page: [597 - 604] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

We review various advancements in small molecule probes, intein-based labeling methods, and the incorporation of synthetic amino acids into proteins for live cell imaging experiments. Finally, recent developments in quantum dots-based labeling are briefly reviewed.

Keywords: bioimaging, fluorescence, native chemical ligation, protein splicing, gfp, small molecules