Abstract

Environmentally method for the synthesis of 1,3-thiazole has been achieved by multicomponent reactions of primary amines, isothiosyanates and alkyl bromides under solvent-free conditions using nanorod ZnO structures as catalyst. These reactions were not performed without catalyst. The catalyst showed significant reusable activity.

Keywords: Alkyl bromides, isothiosyanates, multicomponent reactions, Nanorod ZnO, primary amines.