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Letters in Drug Design & Discovery

Author(s): Lin-Jiong Zhang, Ming-Yan Yang, Zhao-Hui Sun, Cheng-Xia Tan, Jian-Quan Weng, Hong-Ke Wu and Xing-Hai Liu

DOI: 10.2174/1570180811666140610212731

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Synthesis and Antifungal Activity of 1,3,4-Thiadiazole Derivatives Containing Pyridine Group

Page: [1107 - 1111] Pages: 5

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Abstract

Some 1,3,4-thiadiazole derivatives containing pyridine group were synthesized. The structures of 1,3,4- thiadiazoles were confirmed by 1H NMR, MS, and elemental analysis. The title compounds were investigated for antifungal activities. The results showed that some of them exhibited good antifungal activity.

Keywords: 1, 3, 4-thiadiazole, antifungal activity, pyridine, synthesis.

Graphical Abstract